Prosomes and their multicatalytic proteinase activity

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Disruption of prosomes by some bivalent metal ions results in the loss of their multicatalytic proteinase activity and cancels the nuclease resistance of prosomal RNA.

Prosomes are ribonucleoprotein particles constituted by a variable set of about 20 proteins found associated with untranslated mRNA. In addition, they contain a small RNA, the presence of which has been an issue of controversy for a long time. The intact particles have a multicatalytic proteinase (MCP) activity and are very stable; we have never observed autodigestion of the particle by its int...

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ژورنال

عنوان ژورنال: European Journal of Biochemistry

سال: 1992

ISSN: 0014-2956,1432-1033

DOI: 10.1111/j.1432-1033.1992.tb17089.x